Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0009324
Disease: Ulcerative Colitis
Ulcerative Colitis
0.100 AlteredExpression disease BEFREE There were no significant differences in TWEAK levels between the total IBD group and healthy control subjects, nor between UC and CD, or between UC/CD and healthy subjects. 28040992 2017
CUI: C0009324
Disease: Ulcerative Colitis
Ulcerative Colitis
0.100 AlteredExpression disease BEFREE In IBD, inflammation increased the bowel expression of midkine solely in UC, in a manner proportional to the disease clinical activity. 27692729 2017
CUI: C0009324
Disease: Ulcerative Colitis
Ulcerative Colitis
0.100 PosttranslationalModification disease BEFREE The epigenetic changes observed in this study indicate that CD and UC exhibit specific DNA methylation signatures with potential clinical applications in IBD non-invasive diagnosis and prognosis. 25526479 2014
CUI: C0009324
Disease: Ulcerative Colitis
Ulcerative Colitis
0.100 Biomarker disease BEFREE Patients completed the IBD-DI questionnaire and Crohn's and Ulcerative Colitis Questionnaire (CUCQ-8) for assessing quality of life. 28208008 2017
CUI: C0009324
Disease: Ulcerative Colitis
Ulcerative Colitis
0.100 Biomarker disease BEFREE Sulfate-reducing bacteria (SRB) are often isolated from animals and people with ulcerative colitis and can be involved in the IBD development in the gut-intestine axis. 31614543 2019
CUI: C0009324
Disease: Ulcerative Colitis
Ulcerative Colitis
0.100 Biomarker disease BEFREE To investigate whether variants in NOD2/CARD15 and TLR4 are associated with CD and ulcerative colitis (UC) in a genetically admixed population of Rio de Janeiro, where IBD has continued to rise. 27107867 2016
CUI: C0009324
Disease: Ulcerative Colitis
Ulcerative Colitis
0.100 Biomarker disease BEFREE Change in paradigm: impact of an IBD medical home on the outpatient management of acute severe ulcerative colitis. 31586953 2019
CUI: C0009324
Disease: Ulcerative Colitis
Ulcerative Colitis
0.100 Biomarker disease BEFREE A total of 237 physicians attended training courses on IBD endoscopic scoring systems, and they independently scored a set of IBD endoscopic videos for ulcerative colitis [with Mayo endoscopic subscore], post-operative Crohn's disease [with Rutgeerts score] and luminal Crohn's disease (with the Simple Endoscopic Score for Crohn's Disease [SESCD] and Crohn's Endoscopic Index of Severity [CDEIS]). 28453758 2017
CUI: C0009324
Disease: Ulcerative Colitis
Ulcerative Colitis
0.100 Biomarker disease BEFREE Six [13%; CD = 3, ulcerative colitis (UC) = 2, IBD-unclassified (IBD-U) = 1] of the 48 children (CD = 25; UC = 23) with IBD have IO-IBD. 28082818 2016
CUI: C0009324
Disease: Ulcerative Colitis
Ulcerative Colitis
0.100 Biomarker disease BEFREE Breast milk specimens from HC [n = 17] and IBD [n = 31 for Crohn's disease [CD]; and n = 41 for ulcerative colitis [UC]; were collected at 3 and 6 months postpartum [PP3] and [PP6], respectively.Faecal samples were also collected. 30418545 2019
CUI: C0009324
Disease: Ulcerative Colitis
Ulcerative Colitis
0.100 Biomarker disease BEFREE Crohn's disease and ulcerative colitis, collectively known as IBD, are chronic inflammatory disorders of the gastrointestinal tract. 29789682 2018
CUI: C0009324
Disease: Ulcerative Colitis
Ulcerative Colitis
0.100 Biomarker disease BEFREE Clinical efficacy and safety of golimumab in biologically experienced and naive patients with active ulcerative colitis: A real-life experience from two Italian IBD centers. 30039533 2018
CUI: C0009324
Disease: Ulcerative Colitis
Ulcerative Colitis
0.100 Biomarker disease BEFREE Predominant expression of the V delta 1 subtype was demonstrated in the small intestine of patients with coeliac disease and in the inflamed colon of patients with inflammatory bowel diseases (IBD: ulcerative colitis and Crohn's disease) as well as in colon biopsies taken from macroscopically normal areas of colon. 7813110 1995
CUI: C0009324
Disease: Ulcerative Colitis
Ulcerative Colitis
0.100 Biomarker disease BEFREE The expanding knowledge of the role of genetic variants involved in the susceptibility to IBD heralds an era of disease categorization beyond Crohn's disease and ulcerative colitis. 24345887 2014
CUI: C0009324
Disease: Ulcerative Colitis
Ulcerative Colitis
0.100 Biomarker disease BEFREE We used the University of Manitoba IBD Database to identify all persons in a Canadian province with CD or UC who received anti-TNF therapy between 2004 and 2016. 31211836 2019
CUI: C0009324
Disease: Ulcerative Colitis
Ulcerative Colitis
0.100 Biomarker disease BEFREE In a nationwide cohort study we identified 4695 children [< 18 years] diagnosed with incident IBD in 2002-2014 through the Swedish Patient Register [ulcerative colitis: n = 2295; Crohn's disease: n = 2174; inflammatory bowel disease-unclassified: n = 226]. 29029152 2018
CUI: C0009324
Disease: Ulcerative Colitis
Ulcerative Colitis
0.100 Biomarker disease BEFREE Macrophage and dendritic cell subsets in IBD: ALDH+ cells are reduced in colon tissue of patients with ulcerative colitis regardless of inflammation. 26080709 2016
CUI: C0009324
Disease: Ulcerative Colitis
Ulcerative Colitis
0.100 Biomarker disease BEFREE Electronic databases (MEDLINE, EMBASE/EMBASE classic Cochrane CENTRAL register of controlled trials, the Cochrane IBD Group Specialised Trials Register and Clinicaltrials.gov registry) will be searched to identify all randomised placebo-controlled clinical trials of food and drug administration (FDA)-approved biologics for CD and UC (by March 2016). 30782731 2019
CUI: C0009324
Disease: Ulcerative Colitis
Ulcerative Colitis
0.100 Biomarker disease BEFREE The inflammatory bowel disease linkage peak on chromosome 6q is located in the same general region that showed nominal evidence for linkage to IBD in a Belgian genome scan, and the ulcerative colitis linkage peak on chromosome 2q is located in the same general region that showed nominal evidence for linkage to the inflammatory bowel disease, Crohn's disease, or ulcerative colitis phenotypes in four other European/North American genome scans. 15472510 2004
CUI: C0009324
Disease: Ulcerative Colitis
Ulcerative Colitis
0.100 Biomarker disease BEFREE To do a genome-wide gene expression study of active and inactive ulcerative colitis and Crohn's disease (inflammatory bowel disease--IBD) and examine the most differentially expressed genes. 21992413 2011
CUI: C0009324
Disease: Ulcerative Colitis
Ulcerative Colitis
0.100 Biomarker disease BEFREE Median DD in IBD was 3.0 months, it was significantly [P < 0.0001] higher in Crohn's disease [CD] [7.1 months] than in ulcerative colitis [UC] [2.0 months], and did not differ either between the HC and the MC or over the last three decades. 28333328 2017
CUI: C0009324
Disease: Ulcerative Colitis
Ulcerative Colitis
0.100 Biomarker disease BEFREE Primary sclerosing cholangitis [PSC] is an idiopathic chronic disorder of the hepatobiliary system associated with inflammatory bowel disease [IBD], mainly ulcerative colitis [UC]. 28383652 2017
CUI: C0009324
Disease: Ulcerative Colitis
Ulcerative Colitis
0.100 Biomarker disease BEFREE Families with IBD should be counseled that early tobacco use significantly increases the risk of developing CD or, if an ex-smoker, UC at a young age. 17345609 2007
CUI: C0009324
Disease: Ulcerative Colitis
Ulcerative Colitis
0.100 Biomarker disease BEFREE The nine hour overnight urinary excretion of polyethyleneglycol-400 (PEG-400) and three inert sugars (lactulose, l-rhamnose, and mannitol) was used to test the permeation in 47 patients with Crohn's disease of whom 18 had at least one first degree relative with inflammatory bowel disease (2BD) and 52 patients with ulcerative colitis of whom 16 had at least one first degree relative with IBD. 8307453 1994
CUI: C0009324
Disease: Ulcerative Colitis
Ulcerative Colitis
0.100 Biomarker disease BEFREE TRPA1 and TRPV1 expressions were investigated in human colon biopsies of healthy subjects and patients with inflammatory bowel diseases (IBD: ulcerative colitis, Crohn's disease) with quantitative PCR and immunohistochemistry. 25265225 2014